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Which of the following antibodies are a group of identical antibodies because they are made up of identical immune cells that are all clones of a unique parent cell?
a) polyclonal antibodies                    
b) monoclonal antibodies
c) both a and b    
d) none of them

b

Explanation: Monoclonal antibodies (MABs) are a type of targeted drug therapy. These drugs recognize and find specific proteins on cancer cells.


Monoclonal antibodies are typically made by fusing………
a) myeloma cells with sperms from man
b) myeloma cells with ovum
c) myeloma cells with spleen cells from mouse                                         
d) all of these

c

The technique, in which myeloma cells are fused with spleen cells of mouse to produce monoclonal antibodies, is known as……..
a) germ line cell hybridization                          
b) somatic cell hybridization
c) animal tissue culture                                      
d) transgenic modification

b

Explanation: Somatic cell hybridization is the method of choice to separate a chromosome of interest from the full chromosome complement and obtain a permanent source of the chromosome.


n biotechnology, a probe is a florescent or radioactive labeled fragment of…….of variable length (usually 100-1000 base long).
a) DNA                                 
b) RNA
c) both a and b
d) none of them

c

DNA/RNA probes are widely used in diagnosis of many……..diseases?
a) viral                                  
b) bacterial
c) fungal                                               
d) both a and b

d

A technique for correcting defective genes responsible for disease development is called…
a) genetic hybridization
b) animal tissue culture
c) gene therapy  
d) transgenesis

c

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