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During which phase of cell cycle, DNA and histones are completely disorganized from each other?
a) S-phase                  
b) G1-phase
c) G2- phase               
d) mitotic phase

a

Explanation: bit after DNA replication, both DNA and histones begin to organize to become chromosome



The organization of chromosomes occurs in ……..levels.
a) two 
b) three           
c) four
d) five

c

In 1st level of chromosome organization, how many nucleotides of duplex DNA wrap twice around the core of eight histone?
a) 100 
b) 200 
c) 1000           
d) 2000

b

Explanation: two of each H2A, H2B, H3 and Hhistone proteins with DNA forming a complex known as nucleosome. H1 is associated with small segment of DNA called linker DNA between every two nucleosome



What is the thickness of whole DNA molecule?
a) 2 mm          
b) 2cm
c) 2nm
d) 2 µm

c

What is the thickness of nucleosome (the complex of DNA and eight Histones?
a) 20 mm
b) 3cm
c) 10nm          
d) 10µm

c



DNA wrap twice around the core of eight histones proteins to form nucleosome except……
a) H2A
b) H2B
c) H3  
d) H1


d

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